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Journal Articles

Comparison of lifetime mortality risk, incidence risk, and DALYs of baseline cancer rates among countries as a benchmark for radiation-related cancer risk

Hirouchi, Jun; Kujiraoka, Ikuo; Takahara, Shogo; Takada, Momo*; Schneider, T.*; Kai, Michiaki*

Journal of Radiological Protection, 44(2), p.021510_1 - 021510_10, 2024/06

no abstracts in English

Journal Articles

Calculating disability-adjusted life years (DALY) as a measure of excess cancer risk following radiation exposure

Shimada, Kazumasa; Kai, Michiaki*

Journal of Radiological Protection, 35(4), p.763 - 775, 2015/12

AA2014-0479.pdf:1.53MB

 Times Cited Count:16 Percentile:79.15(Environmental Sciences)

This paper has proposed that disability-adjusted life year (DALY) can be used as a measure of radiation health risk. DALY is calculated as the sum of years of life lost (YLL) and years lived with disability (YLD). This multidimensional concept can be expressed as a risk index without a probability measure to avoid the misuse of the current radiation detriment at low doses. In this study, we calculated YLL and YLD using Japanese population data by gender. DALY for all cancers in Japan per 1 Gy per person was 0.84 year in men and 1.34 year in women. When we calculated the ICRP detriment from the same data, DALYs for the cancer sites were similar to the radiation detriment in the cancer sites, excluding leukemia, breast and thyroid cancer. A big advantage over the ICRP detriment is that DALY can calculate the risk components for non-fatal diseases without the data of lethality. This study showed that DALY is a practical tool that can compare many types of diseases encountered in public health.

Oral presentation

A Method of estimate disability-adjusted life years (DALY) as a measure of cancer risk following radiation exposure in Japanese population

Shimada, Kazumasa; Kai, Michiaki*

no journal, , 

In this study, we proposed that disability-adjusted life year (DALY) to estimate radiation cancer risk in Japanese residents. DALY is calculated as the sum of Years of Life Lost (YLL) and Years Lived with Disability (YLD). We separately calculated the excess absolute risk for cancer incidence based on the Excess Relative Risk (ERR) and Excess Absolute Risk (EAR) models. Cancer-specific incidence, mortality rates, and the survival fractions exceeding 5 years have been based on data from the National Cancer Center in Japan. The cancer-specific incidence and mortality rate statistics were from 2010 in Japan; the survival fractions exceeding 5 years were from 2003 to 2005 in Japan. We used disability weights (DW) of cancer according to stage diagnosis/therapy in the WHO table. Table illustrates the results of DALY for each cancer site for Japanese after exposure at 1 Gy dose per 1000 persons. Furthermore, the ratio of DALY for each cancer site per DALY for all solid cancers and the ratio of YLL per DALY for each cancer are shown in this Table. We calculated the DALY of radiation solid cancer risk as a measure of health risk. DALY can be a practical tool that can compare many types of diseases encountered in common public health.

Oral presentation

Analysis of the risk index of radiation health using Disability-Adjusted Life Years (DALY)

Shimada, Kazumasa; Kai, Michiaki*

no journal, , 

In this study, we proposed that Disability-Adjusted Life Year (DALY) to estimate radiation cancer risk in Japanese residents. Lifetime cancer mortality, incidence rate, and lives lost have been the previous indices of health risk associated with radiation protection. ICRP defined the detriment in Publication 60 by considering non-fatal cancers and the number of lives lost due to the difference in latent times. However, the detriment has the disadvantage that it can neither be appropriately interpreted nor used. Therefore, the common index is required to discuss health risk of radiation and the others. As a risk measure of both common health and environmental health, there is a disability-adjusted life year (DALY) that is developed from concepts of life lost. DALY was developed by Harvard University in 1990 and was further adopted to establish an order of priority for health issues by the World Health Organization (WHO). In this study, we calculated DALY to estimate radiation cancer risk and compared this with the radiation detriment to discuss the effectiveness of DALY.

Oral presentation

A Benchmark for comparing radiation-related cancer risk among countries; Baseline cancer rates of incidence and mortality

Hirouchi, Jun; Kujiraoka, Ikuo; Takahara, Shogo; Takada, Momo*; Kai, Michiaki*; Schneider, T.*; Lecomte, J.-F.*

no journal, , 

no abstracts in English

Oral presentation

Application of disability-adjusted life years (DALYs) in radiation protection

Hirouchi, Jun; Kujiraoka, Ikuo; Takahara, Shogo; Takada, Momo*; Kai, Michiaki*; Schneider, T.*; Lecomte, J.-F.*

no journal, , 

no abstracts in English

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